BeaBiochemist

A ��Ҵ�ý�ƽ�� Biochemistry Alumna Quickly Establishing a Career in Medicine: Caitlin Bell

Jessica Helzer — Tue, 28 Apr 2026 13:55:25 +0000

A ��Ҵ�ý�ƽ�� Biochemistry Alumna Quickly Establishing a Career in Medicine: Caitlin Bell Jessica Helzer Tue, 04/28/2026 - 07:55

CU BOULDER BIOCHEMISTRY: THE PLACE FOR ME

I had developed a love of science through my advanced chemistry and physics courses at East High School in Denver. Even though I sat toward the back and was told I talked too much by the teachers in those classes, I found myself drawn to the nature of systematic problem solving and testing inherent in the field. So, knowing that I wanted to pursue something in the area of biochemistry or molecular biology and being lucky enough to be awarded the Boettcher scholarship, I chose to come to CU for my degree and to hopefully gain experience that would clarify how I wanted to use science in my career.

BIOCHEMISTRY AS INSPIRATION

I didn't have a set plan when starting at CU for exactly what I wanted to do. Knowing I liked science and was okay in the classes meant that I thought about a PhD as an option. I also grew up in a family where there were some physicians so that was also in--> on my mind as a possibility. So, in addition to time in the lab, I was able to get some experiences in healthcare volunteer work and shadowing, which I enjoyed but were not overwhelmingly convincing to me for a career as a doctor. What I, for better or worse, found most compelling to choosing a direction during college was the experience of my sister getting sick and my family and personal feelings of helplessness both from a medical and systems perspective. So there was a lot of meaning for me created around the idea of being able to alleviate these feelings of powerlessness. And how could the more direct practice of scientific and biochemical research fit into that? I think what took me a long time (perhaps too long) to fully appreciate was how the scientific discovery and story I worked on in the lab more broadly could be applied to treatment of diseases like cancer or more rare orphan conditions that didn't have treatment options currently available. So ultimately I became most interested in how fundamental discoveries could be translated to the clinical space.

CONNECTIONS MAKE A DIFFERENCE: GAINING REAL-WORLD EXPERIENCE

A family friend had happened to become an acquaintance with Dr. Thomas R. Cech while he was at HHMI and suggested I look into working in his lab as a form of practical experience when starting my studies. So as a freshman I started working in the lab, dutifully making plates, cell culture media, and buffers, and timidly using the autoclave. Over time I started working with one of the postdoctoral fellows, learning how to perform site directed mutagenesis of plasmids, transforming bacteria, and generating sizeable amounts of mutated enzyme for a variety of assays. A screening process now referred to by Dr. Cech as "obsolete" and "we would never do this now." But the exercise of getting to take exceptional chemistry and biochemistry courses from faculty, paired with the real-world experience of generating hypotheses and designing and running experiments to test relevant and important scientific questions, allowed me to gain a broad appreciation of the field. With more time I was actually able to meaningfully contribute effort and usable data to his project, understanding how multiple years of work and many experimental iterations came together to ultimately form a full scientific story. This is the story that was ultimately published in Nature and served as the basis for my honors thesis, my first real exercise in scientific writing. Others credited from ��Ҵ�ý�ƽ�� include: Nandakumar J (this was the amazing postdoc I worked with, now on faculty at Michigan), Weidenfeld I, Zaug AJ, Leinwand LA, Cech TR.

First Published Paper - Nature 2012 Dec 13

COMING FULL CIRCLE FOLLOWING CU UNDERGRADUATE PROGRAM: ASSISTANT PROFESSOR OF CARDIOLOGY - CU ANSCHUTZ

So, after a lot more school and a lot more training at different places across the country (Vanderbilt, Dana Farber, Stanford) with that ongoing--> an ongoing interest in scientific and medical research, I'm now back home in Colorado with an actual job as an Assistant Professor of Cardiology at the medical center. I have developed an expertise in an area of medicine called cardio-oncology where I see patients who have experienced cardiotoxic side effects from their cancer therapy, have cardiovascular disease that needs management during their cancer therapy, or cancer survivors looking for guidance on cardiovascular health. This helps to inform my research program that works to understand how and why cancer patients have worse cardiovascular disease even after cure, and ways we can use new and existing therapies to change this. This has allowed me to keep working in basic and translational science, pilot and Phase 1 clinical trial work, and preclinical and clinical biomedical industry consulting work. Though I draw on a lot of different training experiences I've had in my current career, there are fundamentals I learned while at CU that I use every day whether that is troubleshooting a basic assay in the lab with my technician, thinking critically about optimal experimental design, assessing important literature coming out in the field, or thinking about how to best train and prepare future physicians and scientists.

ON BEING SUCCESSFUL IN BIOCHEMISTRY

Consistently showing up and doing your best is a large portion of the battle. Working in the Cech lab was one of the most formative experiences for me while in college, and it was later revealed to me that half of why I was able to spend a full 4 years there was the fact that I kept showing up and reliably working hard. The other half was that Dr. Cech had forgotten to ask me to stop coming, his words.

Stay flexible, open minded, and reflective, even if you think you have it all planned out. You have likely had and will continue to have experiences that change your perspectives or motivations.
Working in science and research is a team sport; use your time at CU to help think about what excites you about that team sport and what skills you want to bring to the table going forward. Because what you've learned so far is relevant, applicable, and can be transformative.

Caitlin Bell, MD

Caitlin Bell, MD CU Anschutz Profile

Bell Lab - CU Anschutz

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A Biochemistry Undergraduate Inspired and Mentored by Two PIs and Moving Toward a Chemical + Biology Interface: Liora Goldstein

Jessica Helzer — Fri, 24 Apr 2026 20:21:28 +0000

A Biochemistry Undergraduate Inspired and Mentored by Two PIs and Moving Toward a Chemical + Biology Interface: Liora Goldstein Jessica Helzer Fri, 04/24/2026 - 14:21

CU BOULDER: THE PLACE FOR ME

From an early age, I was drawn to both biology and chemistry, and I became interested in how these disciplines intersect through biochemistry. I chose to pursue my undergraduate studies at the University of Colorado Boulder because of my love for the state of Colorado and the strength of its close-knit yet accomplished Department of Biochemistry. As an R1 research institution, ��Ҵ�ý�ƽ�� offered me the opportunity to engage in meaningful research early in my academic career, which was also a key component in my decision.

I began my research career in 2022 in the laboratory of Dr. Jeffrey Cameron, where I studied the life-sustaining characteristics of cyanobacteria using inducible CRISPRi methodologies. Following Dr. Cameron’s passing in 2024, I continued my research training in the laboratory of Dr. Karolin Luger, where I investigated interactions between the transcriptional cofactor TRIM28 and chromatin. My research interests include chromatin biochemistry, structural biology, drug development, and cancer research.

BIOCHEMISTRY AS INSPIRATION

I am fundamentally inspired by the interconnectedness of molecular systems and biochemical pathways. I find it intriguing to problem solve how these two concepts are related. A unique quality to me is my interest to view science through an artistic creative lens, specifically, my notes are filled with hand-drawn molecular diagrams that help me connect artistic principles with biochemical concepts. This interrelationship between art and science for me has defined my individual approach to biochemical research.

My journey as a scientist has been shaped by Dr. Cameron, whose mentorship and passion for research continues to influence my academic path and personal interests. I have also received UROP funding for my research for the past three years.

CHARTING MY OWN PATH: CU BIOCHEMISTRY + GRADUATE STUDIES

I hope my college experience in biochemistry will give me a deeper understanding of the physical mechanisms underlying the natural world, allowing me to explore possible therapeutics to treat disease. I am interested in bringing an appreciation for the artistic and creative aspects of biochemistry into my graduate studies.

As I enter graduate school, I look forward to exploring diverse areas within structural biology. While I have a strong interest in biology from my time here at ��Ҵ�ý�ƽ��, I am eager to investigate how structural principles extend to other biological systems.

“I am deeply committed to teaching and mentoring and played an active role in undergraduate education through the Learning Assistant program as an LA and an LA mentor at ��Ҵ�ý�ƽ�� and as a teaching assistant for Organic Chemistry I.”

Biochemistry Profile: Liora Goldstein

The Department of Biochemistry is excited to congratulate Liora Goldstein as she approaches the Spring 2026 commencement -- earning a BA in Biochemistry, graduating with Latin Honors as Summa Cum Laude + achieving acceptance into Johns Hopkins University for the Fall 2026 semester within their Chemical + Biology Interface PhD program!

We look forward to staying in touch with her and seeing where her path takes her!

Luger Lab

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An Industry Experience Shaped an Interest in Cancer Research: Kristyn Hayashi

Jessica Helzer — Fri, 10 Oct 2025 13:12:03 +0000

An Industry Experience Shaped an Interest in Cancer Research: Kristyn Hayashi Jessica Helzer Fri, 10/10/2025 - 07:12

MY DISSERTATION & THE POTENTIAL OUTCOMES

I’m currently studying MAPK signaling thresholds using mass spectrometry proteomic and phosphoproteomic approaches in Dr. Natalie Ahn’s lab. I developed my interest in cancer research, cell signaling and systems biology before coming to grad school. My time working in industry research (AbbVie - formerly Stemcentrx) really solidified my love of science, helped focus my research interests, and better prepared me for grad school.

Being selected in 2021-2023 (renewed in 2025) to participate as a trainee on the NIH sponsored T32 Graduate Training Program in Signaling and Cellular Regulation has been a great experience. I really appreciated the cross-disciplinary approach and feel it fosters an interdepartmental sense of community, building connections between the Biochemistry and the Molecular, Cellular & Developmental Biology departments at ��Ҵ�ý�ƽ��.

WHERE I’M HEADED NOW

I hope my grad school training will broaden my scientific understanding to better develop a scientific question and think critically. I love the problem-solving aspect of research, being able to troubleshoot and design my own experiments. I’ve gained more computational skills during my graduate training that I hope to continue using and expand on in my future career.

After graduating, I hope to continue studying cancer research and help develop therapeutics in an industry setting. I hope my science eventually helps patients.

“A highlight of my CU Biochemistry graduate school experience, in addition to my research program, was supporting the Peer-to-Peer (P2P) Mentoring program as a committee leader and helping new and ongoing graduate students navigate their CU Biochemistry path.”

WHY I SELECTED CU BOULDER

My career hasn’t always been a straight path in academia. After getting my undergraduate degree, I lived in South Korea for a year teaching English. During this time, I experienced a lot of personal growth but ultimately realized I missed science. Afterwards, I worked in several different biotech companies in the SF Bay Area. While I gained a lot of important skills, I realized I wanted to better contribute and guide our research goals. I felt the training from a PhD program would better prepare me for a career in scientific research.

I was excited about the research at ��Ҵ�ý�ƽ��, but what really sold me were the mountains and outdoor activities, particularly snowboarding and hiking. Boulder’s a great place to live and I felt the grad students I met during recruitment had a good work life balance.

Ahn Lab
PhD Candidate 2025: Biochemistry

AY24-25: P2P Mentoring Program, Committee Chair
2021-2023 + 2025: NIH Graduate Training Program in Signaling and Cellular Regulation
B.S. Molecular & Cellular Biology, Johns Hopkins University

Download Kristyn's ��Ҵ�ý�ƽ�� Biochemistry Journey

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A Biochemistry Undergraduate with Boundless Energy: Asher Ferreira

Jessica Helzer — Wed, 17 Sep 2025 20:35:10 +0000

A Biochemistry Undergraduate with Boundless Energy: Asher Ferreira Jessica Helzer Wed, 09/17/2025 - 14:35

Asher Ferreira spent this past summer in the Summer Undergraduate Research Program (HHMI SURP) at MIT. Outside of working on a double major (Biochemistry with the recent addition of Chemistry), Asher is Vice President of the Science Community Outreach Program and Education (S.C.O.P.E.) program, which aims to increase science identity and access for middle school students. He is also Vice President of the CU Trampoline Club... now you understand why we know he has "boundless energy"!

CU BOULDER = THE PLACE FOR ME
I chose to do biochemistry at ��Ҵ�ý�ƽ�� for several reasons. One is the abundance of world class research all set against a backdrop of beautiful mountains. Another is the culture of supporting undergraduate research endeavors and the accessibility of laboratory research. Also, as someone who wants to pursue a career in biotech, having a designated biotechnology building with 3 floors of cutting-edge research labs was a big plus.

I just declared a major in chemistry in addition to biochemistry! I recently realized that I can’t feel as confident in my knowledge if I don’t have a deeper understanding of the latter half of biochemistry. Also, I found that I really enjoy organic chemistry and after my experience researching metalloenzymes at MIT this summer I have become fascinated with bio inorganic chemistry. I’m taking this next semester as a sort of trial run to see how much I enjoy pure chemistry and the corresponding bench work.

UNDERGRADUATE RESEARCH OPPORTUNITY: INVALUABLE KNOWLEDGE
I hope a biochemistry degree gives me the toolset and confidence to propose solutions to complex biochemical problems and invent new assays and methods for discovery. I think what this program has already allowed me to do in two years is incredible and makes me excited for the latter half of my college experience.

I believe living matter is the most fascinating phenomenon in the universe. It’s endlessly complex and adaptive: it can facilitate novel chemical reactions and survive across an enormous range of environments. Biochemistry is life at the smallest possible scale and is therefore the root cause of all diseases and afflictions. The sheer complexity of life at its most basic components means there’s so much space to invent and discover. Biochemistry is an infinite sandbox for my curiosity, and through it I can better understand - or at least investigate - life systems and disease.

Asher Ferreira with KRIOS EM

“I am really interested in intellectually contributing to the fight against disease, whether it’s through industry or academia. More specifically, I want to design and develop new treatments using my knowledge of biochemistry and biochemical research. Regardless of the specifics, this will involve earning a PhD. A doctorate would open a lot of options for me such as starting my own biotech, joining a larger pharmaceutical company or biotech in R&D, or continuing my journey in academia. I also think that teaching biochemistry as a professor would be really fun.”

MY LIFE'S JOURNEY

Asher Ferreira, Vice President of CU Trampoline

The impetus for my curiosity with biochemistry was being diagnosed with type 1 diabetes when I was nine. Part of why I want to fight disease so much is because I know how it feels to wake up one day and have your entire world be turned upside down by a biochemical phenomenon completely outside of your control.

CHARTING MY OWN PATH: CU BIOCHEMISTRY SUPPORT
At the end of the spring semester, I reached out to Dr. Catherine Drennan at MIT with my CV and a cover letter to apply to work in her lab that summer. Coincidentally, HHMI reinstated its Summer Undergraduate Research Program (HHMI SURP) at the same time, so she nominated me for it.

This couldn’t have happened without my current PI at ��Ҵ�ý�ƽ��, Dr. Karolin Luger, vouching for me.

I’m from Boston so I biked to MIT every day from home which was really nice. I really appreciated how interdisciplinary the lab was, I met grad students and post docs with backgrounds in organic, inorganic, and biochemistry - all fields I’m interested in exploring! I enjoyed my independence this summer; I got to design and conduct my own experiments as well as invent my own methods. My big takeaways from this experience are: science should always be done creatively, and a positive work environment and culture is the most important criterion for choosing a lab.

MY GRATITUDE AND FORWARD-THINKING

“I am really honored to have been awarded the Bob and Dickie Lacher scholarship in AY2024-2025 and again this academic year. This year I’ve shifted my focus towards national awards such as the Goldwater and Astronaut scholarships. I also want to enter my name in the competition for the DOORS program to make connections in the biotechnology industry. Since US-based biotechnology and research is currently suffering from governmental funding cuts, I’m considering applying to UK-based scholarships such as the Rhodes and Gates-Cambridge.”

Biochemistry Undergraduate Profile: Asher Ferreira

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A Well-rounded Biochemist with an Interest in Classics and International Experiences: Damian Sonsino

Jessica Helzer — Tue, 27 May 2025 16:07:03 +0000

A Well-rounded Biochemist with an Interest in Classics and International Experiences: Damian Sonsino Jessica Helzer Tue, 05/27/2025 - 10:07

Damian Sonsino has embraced his full experience at ��Ҵ�ý�ƽ�� as an undergraduate and now an alumnus, selecting Biochemistry as his primary major, while adding a second major in Classics and a minor in Hebrew and Israel Studies. And... he did all of this while earning top honors - both in academic achievements and recognition from faculty and peers alike. Let's see what his path looked like!

CU BOULDER - A PLACE THAT FEELS LIKE HOME

I chose to attend ��Ҵ�ý�ƽ�� because I grew up in Colorado, graduating from Gilpin County Undivided High School, and loved the atmosphere, the beautiful campus, and the opportunity to be able to explore options outside of my major. CU offers programs in pretty much anything you could ever want to do, and I actually declared a second major in Classical Studies and a minor in Hebrew/Israel Studies since beginning my studies here. There aren’t a lot of schools that can offer that and I am super happy to have been able to study a broad range of subjects that I was interested in. I didn’t know much about biochemistry or the department here at CU, I just liked biology and chemistry in high school. However, after taking BCHM classes, meeting professors, and conducting research here, I absolutely love the program. I think that the faculty are very knowledgeable, accomplished, and friendly, and the facilities for the BCHM department are excellent.

UNDERGRADUATE RESEARCH OPPORTUNITY = INVALUABLE KNOWLEDGE

I think that the biggest source of inspiration for me in Biochemistry is the amount that we don’t know. I am absolutely fascinated by the mechanisms, structures, and pathways that we already know, and learning those is super fun for me. However, in class or in the research lab, I am constantly reminded of all of the things we don’t know. I have faith that biochemical techniques will continue to be improved upon and allow us to keep learning more about ourselves and the natural world.

I defended my honors thesis in the Spring 2025 semester, receiving a Latin Honors designation of Summa Cum Laude and I won the Biochemistry Department’s Best Poster Award at the Undergraduate Research Symposium - April 2025.

The Biochemistry Department celebrates Damian's achievements as he finished his ��Ҵ�ý�ƽ�� career with the following degrees:

BA in Biochemistry
BA in Classics
A minor in Hebrew & Israel Studies

MY LIFE’S JOURNEY

I studied abroad in beautiful city of Athens, Greece in the Fall 2024 semester— just one of the many perks of studying at ��Ҵ�ý�ƽ�� is the robust and extensive study abroad program! I also think that research has been a huge component of my time here at CU. I started in an organic chemistry laboratory in the Spring 2023 semester and worked there through the summer, transitioning to my current biochemistry laboratory in Fall 2023. I am super lucky and thankful to have been working on research in the Luger Lab since then, and I am eternally grateful to the Luger Lab and my graduate student mentor for the opportunity and guidance in developing valuable lab skills and gaining experience in the field of biochemical research. Currently, I am hoping to take a gap year and work at a biotech or related company to learn more about non-academic research. I am undecided on whether or not I will be attending graduate school, but I believe that my college experience in Biochemistry will allow me to contribute to the scientific community and give me the tools I need to pursue whatever opportunities, careers, or further interests I may have.

In Academics

In Damian's pursuit of a BA in Biochemistry, he was named this year's American Institute of Chemists Student Award (as voted by faculty). Starting in Spring 2023 and continuing through this spring (2025) he was on the Arts and Sciences Dean's List. In Summer 2023 he received an Undergraduate Research Opportunity Grant (UROP).

Biochemistry Profile: Damian Sonsino

Damian plans to take a "gap year" to work in the bioscience industry and we know wherever his path takes him, he will be a significant and dedicated contributor.

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Individual Talent Embracing the Power of a Team: Mila Stanojevic

Jessica Helzer — Fri, 14 Mar 2025 17:15:42 +0000

Individual Talent Embracing the Power of a Team: Mila Stanojevic Jessica Helzer Fri, 03/14/2025 - 11:15

Mila Stanojevic was on a path to ��Ҵ�ý�ƽ�� as a ranked member in the German top 150 tennis players and a high school graduate of the highly regarded Löwenrot Gymnasium in Heidelberg, Germany. The strength of academic programs offered here plus the beauty of Boulder were top of Mila's list - plus - the tennis team wanted her. She has continued to be a stand-out star - both on the court and in the academic research lab.

Heidelberg, Germany to ��Ҵ�ý�ƽ��: A Fruitful Choice

Born and raised in Germany before moving to Boulder for college, Mila's journey as an
international student-athlete at CU has been incredibly rewarding. She selected the Department of Biochemistry at ��Ҵ�ý�ƽ�� for its strong faculty - giving her the opportunity to learn from amazing professors who are not only leaders in the Biochemistry field but also care for their students’ success. She attributes their passion for teaching and mentorship to creating a great learning environment where she personally felt encouraged to grow her scientific understanding.

Their support has played a crucial role in shaping her academic journey and sparking her curiosity for biochemistry. In addition, the department offers great undergraduate research opportunities where she feels very fortunate to join Dr. Roy Parker’s lab. Individual success and development are strongly supported in the department of Biochemistry, which she says has helped her become a better scientist.

Undergraduate Research Opportunity: Invaluable Mentorship

Mila knew, going into her senior year of college, that she wanted to gain more research experience and sought out an opportunity to join a lab for a summer internship. In Dr. Parker’s lab her research focus is looking at a protein called G3BP1, which is an essential regulator of cellular RNA metabolism. The main known functions of G3BP1 are regulating RNA stability and translation in the cytoplasm. Upon stress, G3BP1 also forms cytoplasmic stress granules, a type of membranelles assembly that forms through the biophysical process of condensation. Her main goal is to understand the mechanism of G3BP1 nuclear- cytoplasmic localization in the cell.

She spends 40 hours per week working in the lab during the summer and while it is a lot of hard work spent in the lab it is also the most fun experience at the same time. One of the biggest reasons she spends so much time in the Parker lab is the incredible mentorship she is given. The guidance and support from experienced researchers created an environment where she felt encouraged to ask questions, think critically, and push herself to improve. Learning something new each day, whether it was troubleshooting an experiment, analyzing data, or perfecting a new technique, made the experience truly enriching. This experience made it clear that she wanted to pursue a career in research.

Blending Success in an Individual Sport into Athletic and Scientific Teamwork

Mila was motivated to find a strong team environment where she has the opportunity to learn from the people around her. Engaging with such a diverse and driven group has taught her the value of collaboration, support and teamwork. Coming from an individual sport, her focus was always on personal success and by transitioning to college athletics, where teamwork is essential, she has found an incredibly valuable experience. She realizes that this lesson translates seamlessly into the research setting where, while each person works on their own project, the true strength of a lab comes from an environment built on teamwork, respect, and mutual support. Embracing this mindset has not only enhanced her experience as an athlete but has also shaped the way she approaches scientific research and collaboration.

In Tennis

In her senior year, Mila Stanojevic is an accomplished member of the ��Ҵ�ý�ƽ�� Women's Tennis team - leading the team in her junior year in doubles and singles wins while being recognized with the ITA Mountain Region Arthur Ash Leadership and Sportsmanship Award; named the No. 2 singles player by ITA in the mountain region and the No. 4 doubles team with Elys Ventura; and after the season she was named honorable mention All-Pac-12.

CU Athletics Profile: Mila Stanojevic

In Academics

In Mila's pursuit of a BA in Biochemistry, she was named to the A&S Dean's List for Fall 2021. She was named an ITA All-Academic Scholar Athlete in her freshman year (2021) and named to the Pac-12 Academic Honor Roll.

Biochemistry Profile: Mila Stanojevic

We are excited to see where Mila's research and tennis career leads her after this spring's commencement. No matter where she goes, we know success will follow!

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Paving the Way in Research for Diverse Perspectives: Meg Palacio

Anonymous — Wed, 15 Nov 2023 22:20:43 +0000

Paving the Way in Research for Diverse Perspectives: Meg Palacio Anonymous (not verified) Wed, 11/15/2023 - 15:20

Leading as an Inclusive Researcher

Advancing diversity, equity, and inclusion of historically excluded students in STEM has been a large part of my identity and effort throughout my graduate school journey. As a Chicana, I recognize the barriers imposed upon disadvantaged groups and know that I would not be where I am today without the aid of programs that increase support for diverse students in science. I felt a responsibility to give back to the same community that helped me to succeed as a young researcher. So, I have been involved in various outreach and mentoring programs such as the Society for the Advancement of Chicano and Native Americans in STEM (SACNAS), Peer-2-Peer mentoring, Summer Multicultural Access to Research Training Program (SMART), Longmont High School SMART Program, STEM Routes, and the Uplift Program. I also co-founded and was the former chair of the Biochemistry Department’s DEI committee. Outreach work is what can inspire the next generation of scientists and it is critical that we create an inclusive environment for all identities to be able to thrive.

My Research: Biochemistry for Creating New Tools for Human Health

My research focuses on elucidating the role of biomolecular condensates in transcription regulation. Biomolecular condensates are membraneless liquid droplets that possess a high concentration of local proteins and/or nucleic acids. These condensates offer spatiotemporal control of protein function and could be utilized by the cell to regulate processes such as transcription. Specifically, most of my efforts have focused on developing a fluorescent assay to simultaneously visualize in real-time condensate formation and human RNA polymerase II transcription using a defined reconstituted in vitro system. I knew this project was a great fit for my thesis research because it combined researching the regulation of a fundamental process with the development of a new method or tool. Additionally, the implication of biomolecular condensates in coordinating transcription is a relatively new idea and subsequently, there are a lot of available questions that need to be addressed so we can better understand the underlying mechanism. Finally, I also find studying human transcription intriguing. It a complex orchestration of a multitude of proteins and nucleic acids where the precise timing is critical for proper gene expression.

My Life's Journey

Biochemistry truly fascinates me, every organism surrounding us survives because of all these thousands of intricate biochemical interactions. I am inspired by the idea that I could be someone who contributes to understanding how these interactions regulate processes that give rise to life. I chose ��Ҵ�ý�ƽ�� because it felt like an environment where I could succeed. Graduate students here appeared to be genuinely happy. They were working hard in lab and simultaneously enjoying their weekends hiking or spending time with friends. These students were publishing in top journals and still finding time to enjoy life. That dynamic is exactly what I wanted in a program. Additionally, the research in the biochemistry department and the CU community is astounding and the faculty are easy to talk to despite their impressive backgrounds. Plus, who wouldn’t love the Rockies in their backyard?

Meg looks to go above and beyond to provide resources for causes where she's directly plugged in, “I hope to secure additional funding for causes important to me and one of those programs is the Longmont High School SMART Program, an afterschool program in a largely Hispanic community that exposes students to protein structure, function, and modeling.” Download Meg's ��Ҵ�ý�ƽ�� Biochemistry journey.

The Taatjes Lab - BCHM

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A Creative and Community Minded Researcher - Clair Huffine

Anonymous — Tue, 26 Sep 2023 20:57:20 +0000

A Creative and Community Minded Researcher - Clair Huffine Anonymous (not verified) Tue, 09/26/2023 - 14:57

Clair Huffine is a 2025 PhD candidate in the Cameron Laboratory. She recently won the 2023 Biophysics Supergroup Outstanding Research Presentation Award; is a 2023 P.E.O. SCHOLARS Award applicant; and in 2022 was an NIH/CU Molecular Biophysics trainee and received Honorable Mention for GRFP - the NSF Graduate Research Fellowship Program.

A Creative and Community-minded Researcher

Giving back gives me energy. In addition to board service with S.C.O.P.E (Science Community Outreach Program and Education), I co-founded QSci: Queers in STEM in order to build a thriving community for LGBTQ+ students, staff, and faculty. Additionally, I am a member of P.E.O., a women’s philanthropic organization whose mission is to fund women’s education at all levels, high school to graduate school. With a love for all things green, I spend my weekends backpacking, tending my jungle of houseplants (complete with my “jungle-cat” Kiki), or fly fishing. I also work as a freelance artist, primarily creating digitally painted landscapes or graphic design work for board games. These skills have been transferable to my scientific career with creating compelling scientific figures for my papers and presentations, increasing community engagement with monthly QSci Posters, and crafting memorable and attractive logos for S.C.O.P.E. My portfolio can be found at clairhuffine.com.

Research: Biochemistry for Climate Change

Bacterial cells are often thought of as lacking subcellular organization. However, bacteria do in fact possess both membrane-bound regions as well as, unique from eukaryotes, protein encapsulated regions in order to accomplish incredible biochemical feats. In Dr. Jeffrey Cameron’s lab, I use time lapse fluorescence microscopy to track the redox state inside the carboxysome, which are protein-encapsulated bacterial microcompartments that house the CO2-fixing machinery for cyanobacteria (commonly known as blue-green algae) and allow them to efficiently remove CO2 from the atmosphere and convert it into sugars and biomass. Having always been driven by the plight of climate change, I hope to provide insight into this CO2-capturing mechanism to ultimately offset increasing atmospheric CO2-levels and slow climate change. I plan to pursue a career focused on addressing climate change through applied research and scientific outreach.

My Life's Journey

I grew up in northern Virginia and with a biology and chemistry degree in hand and moving from one mountain range to the next, I began my graduate degree at the University of Colorado Boulder the Fall of 2020. I wanted to pursue my graduate degree that held inter- and intra-lab teamwork in science as an ideal. I couldn’t help but notice how collaborative and welcoming the scientific environment at ��Ҵ�ý�ƽ�� was. Students and faculty alike were enthusiastic to share their work, make new interdisciplinary connections, and support their peers in any way possible. I joined through the Interdisciplinary Quantitative (IQ) Biology program, which focuses on crossing disciplinary boundaries, encouraging collaboration, and developing computational skill sets.

Clair has a volunteer mindset about life, “Science does not occur in a vacuum; dissemination of research and engagement of the wider community is essential for scientific progress. As such, I have volunteered time across several organizations to foster connections, act as a scientific liaison, and spark excitement about cutting edge research driving science forward..” Not to mention, when she's not in the lab, Clair is using her creative talents to support interesting graphics for student-led groups she is involved in, as well as creative illustrations for scientific papers. Download Clair's ��Ҵ�ý�ƽ�� Biochemistry journey.

The Cameron Lab - BCHM

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Nicole Marie Hoitsma Recognized as a 2023 Damon Runyon Fellow

Anonymous — Wed, 16 Aug 2023 20:32:20 +0000

Nicole Marie Hoitsma Recognized as a 2023 Damon Runyon Fellow Anonymous (not verified) Wed, 08/16/2023 - 14:32

Damon Runyon Cancer Research Foundation awards $3.9 million to exceptional early-career scientists

Nicole Marie Hoitsma, PhD [HHMI Fellow], with her sponsor Karolin Luger, PhD, at University of Colorado, Boulder, has been named one of 13 new Damon Runyon Fellows by the Damon Runyon Cancer Research Foundation.

The Damon Runyon Cancer Research Foundation has named 13 new Damon Runyon Fellows, exceptional postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators. This prestigious Fellowship encourages the nation's most promising young scientists to pursue careers in cancer research by providing them with independent funding to investigate cancer causes, mechanisms, therapies, and prevention. In July 2023, the Board of Directors announced at 15% increase in the Fellowship stipend, bringing the total to $300,000 over the award's four-year term.

“Over the past three decades, the rate of cancer mortality in the U.S. has dropped by a third, saving an estimated 3.8 million lives. This is because of earlier diagnoses, a better fundamental understanding of the genetic changes that take place in a cancer cell, and personalized treatment options like targeted therapy and immunotherapy. Damon Runyon scientists have been a part of each and every one of these advances,” said Yung S. Lie, PhD, President and CEO of Damon Runyon. “We fund the best young talent—risk takers and innovators. I am confident that because of the research being done by our scientists, this trend will continue, such that ultimately cancer will be a fully treatable disease. My optimism is shared by the cancer research community.”

��Ҵ�ý�ƽ�� Hoitsma's Research:

Human cells have complex mechanisms to repair DNA damage, such as that caused by exposure to sunlight or chemical substances. If DNA is not properly repaired, however, it can lead to cancer. In fact, faulty DNA repair has been associated with the initiation and progression of all types of cancer and is often targeted in cancer treatment to stop uncontrolled cell growth. A better understanding of how cells naturally defend against DNA damage will allow for the development of better drugs to treat cancer. Dr. Hoitsma aims to investigate specialized proteins, known as chromatin remodelers, that make damaged DNA accessible for repair. This research will provide insight for the development of novel therapeutic strategies to target these critical pathways. Dr. Hoitsma received her PhD from University of Kansas Medical Center, Kansas City and her BS from South Dakota State University, Brookings.

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A Blooming Scientist: Emily Kibby

Anonymous — Wed, 31 May 2023 14:51:49 +0000

A Blooming Scientist: Emily Kibby Anonymous (not verified) Wed, 05/31/2023 - 08:51

Emily Kibby is a 2025 PhD candidate in Biochemistry in the Aaron Whiteley Research Group. She became an NIH Signaling and Cellular Regulation Trainee in 2020 and in 2021 received a Graduate Teaching Award.

A BLOOMING SCIENTIST

It was only in high school that I started to appreciate chemistry and developed an interest in biology. Up until then I thought I might be a writer and most likely an educator - following in the footsteps of my parents. I became fascinated with understanding the molecular mechanisms that serve as the foundation for life. As is true for many people, I would say the mentorship I’ve received (and given) and the people that I have worked with have been really important parts of my development as a scientist.

RESEARCH: WHERE MICROBIOLOGY MEETS BIOCHEMISTRY

I focus on understanding bacterial immune systems, and investigating the many ways that bacteria have to protect themselves from viruses and other threats. I’ve always been fascinated by the diversity of microbes and the interactions in host-pathogen conflicts, so I love working on a system where both the host and the pathogen are microbes! I think I’m always going to be fascinated by the same things that I love now, but that might expand to looking at the immune systems of other organisms like fungi or archaea, and I anticipate that I will also broaden the strategies I use to answer scientific questions. Genetics are and will always be an incredibly powerful tool to answer the types of question I am excited about, but I’m hoping to learn and use other strategies to investigate microbial conflict systems. Emily’s first first-author paper was just published in Cell (Volume 186, Issue 11, P2410-2424.E18, May 25, 2023)!

MY LIFE’S JOURNEY

I chose the ��Ҵ�ý�ƽ�� Department of Biochemistry because I really loved the collaborative and supportive community found in this department - not to mention the excellent shared facilities and science. I arrived at ��Ҵ�ý�ƽ�� as a first-year grad student Fall of 2019 and managed to experience most of the first year in person before we were shut down due to COVID. Professor Aaron Whiteley started his lab in January of 2020 and after initial rotations, I found the Aaron Whiteley Lab was a great fit with my research interests! Mentoring and teaching are in my DNA and early-on I became involved in undergraduate mentoring, tutoring students through the Student Academic Success Center, and volunteering with Partnerships for Informal Science Education in the Community (PISEC) and the Science Community Outreach Program and Education (SCOPE). Along my journey toward a PhD I’m hoping to learn new skills and strategies for framing, communicating, and investigating exciting scientific questions, and then putting those strategies into practice to do some cool science! Because I have received really helpful mentorship, I wish to continue mentoring others and get other young scientists excited along the way. When I’m not in the lab, I enjoy the many outdoor activities accessible in Boulder, playing volleyball, and other group activities that our community is known for! I hope that my career will lead me to an academic environment where teaching is paramount - but never removed from the joy and application of the research.

Emily has an inquisitive mindset about life, “I just love that biochemistry gives a window to better understand the molecular strategies used by us and other organisms to live. “Life” as we think about it is already so incredible, the fact that we can understand it on a molecular level and that we still have so much to learn has always been really exciting to me. I also love that biochemistry has so many applications for making life on this shared planet better for everyone.” Not to mention, when she's not in the lab, Emily is using her teaching mindset to tutor and mentor undergraduate students and provide support to her fellow graduate students. Download Emily's ��Ҵ�ý�ƽ�� Biochemistry journey.

Aaron Whiteley Research Group - BCHM

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