Supermassive black holes at the center of active galaxies are known as blazars when they are extremely bright and produce powerful jets of matter and radiation visible along the line of sight to the Earth. Blazars can appear up to a thousand times more luminous than ordinary galaxies, and their associated jets are so powerful they can travel millions of light years across the Universe. Blazar jets produce flares of high-energy gamma rays that are detected by ground- and space-based observatories.