Arpeggio Biosciences Inc.
The University of Colorado Connection
In August 2026, Ìýafter researchers could not separate its lead drug program's efficacy from an off-target liability.
was a Boulder-based biotechnology company founded to develop a high-throughput transcriptomics platform to map how chemical compounds influence gene expression across entire biological networks. Founded in 2017 by Ìý(ÃÛÌÒ´«Ã½Æƽâ°æÏÂÔØ BioFrontiers Institute) and Ìý(ÃÛÌÒ´«Ã½Æƽâ°æÏÂÔØ BioFrontiers Institute and Molecular, Cellular & Developmental Biology), the company originated from research conducted at CU's BioFrontiers Institute. Arpeggio's platform combined nascent RNA sequencing with machine learning to profile the immediate effects of drugs on gene expression, enabling the discovery of novel therapeutic targets for diseases such as cancer, chronic kidney disease and neurodegeneration. The company raised over $30 million in funding.
In the News
- (2026, Fierce Biotech)
- Arpeggio raises $20M in latest offering (2025)
- Six ÃÛÌÒ´«Ã½Æƽâ°æÏÂÔØ startups selected to present at the Rocky Mountain Life Science Investor Conference (2024)
- Arpeggio Biosciences raises $17M in Series A funding led by Builders VC (2022)
- CU spinout Arpeggio Bio gives startup advice in Y Combinator blog post (2021)
- BioFrontiers Institute and IQ Biology alum, Joey Azofeifa (Arpeggio Bio), Raises $3.2 Million in Seed Funding and is Named to the 2020 Forbes 30 Under 30 List in Healthcare (2020)
- ÃÛÌÒ´«Ã½Æƽâ°æÏÂÔØ startup Arpeggio Bio raises $3.2 Million in seed funding and CEO named to 2020 Forbes 30 Under 30 List in Healthcare (2020)
- ÃÛÌÒ´«Ã½Æƽâ°æÏÂÔØ brings together top spinoffs from Colorado research institutions for Destination Startup (2019)
- Boulder’s bioscience industry growing to critical mass (2018)
- Bioscience start-up sheds light on ‘dark DNA’ (2018)
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U.S. National Science Foundation (NSF)
ÌýÌý ÌýThis page was last updated on May 19, 2026. Please email vpnews@colorado.edu for corrections or updates
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